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Pervasive polymorphic imprinted methylation in the human placenta
The maternal and paternal copies of the genome are both required for mammalian development, and this is primarily due to imprinted genes, those that are monoallelically expressed based on parent-of-origin. Typically, this pattern of expression is regulated by differentially methylated regions (DMRs)...
Autores principales: | Hanna, Courtney W., Peñaherrera, Maria S., Saadeh, Heba, Andrews, Simon, McFadden, Deborah E., Kelsey, Gavin, Robinson, Wendy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889973/ https://www.ncbi.nlm.nih.gov/pubmed/26769960 http://dx.doi.org/10.1101/gr.196139.115 |
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