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Pervasive polymorphic imprinted methylation in the human placenta

The maternal and paternal copies of the genome are both required for mammalian development, and this is primarily due to imprinted genes, those that are monoallelically expressed based on parent-of-origin. Typically, this pattern of expression is regulated by differentially methylated regions (DMRs)...

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Detalles Bibliográficos
Autores principales: Hanna, Courtney W., Peñaherrera, Maria S., Saadeh, Heba, Andrews, Simon, McFadden, Deborah E., Kelsey, Gavin, Robinson, Wendy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889973/
https://www.ncbi.nlm.nih.gov/pubmed/26769960
http://dx.doi.org/10.1101/gr.196139.115

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