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Flt1/VEGFR1 heterozygosity causes transient embryonic edema

Vascular endothelial growth factor-A is a major player in vascular development and a potent vascular permeability factor under physiological and pathological conditions by binding to a decoy receptor Flt1 and its primary receptor Flk1. In this study, we show that Flt1 heterozygous (Flt1(+/−)) mouse...

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Detalles Bibliográficos
Autores principales:	Otowa, Yasunori, Moriwaki, Kazumasa, Sano, Keigo, Shirakabe, Masanori, Yonemura, Shigenobu, Shibuya, Masabumi, Rossant, Janet, Suda, Toshio, Kakeji, Yoshihiro, Hirashima, Masanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890026/ https://www.ncbi.nlm.nih.gov/pubmed/27251772 http://dx.doi.org/10.1038/srep27186

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