TLR9-ERK-mTOR signaling is critical for autophagic cell death induced by CpG oligodeoxynucleotide 107 combined with irradiation in glioma cells

Synthetic oligodeoxynucleotides containing unmethylated CpG dinucleotides (CpG ODN) function as potential radiosensitizers for glioma treatment, although the underlying mechanism is unclear. It was observed that CpG ODN107, when combined with irradiation, did not induce apoptosis. Herein, the effect...

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Detalles Bibliográficos
Autores principales: Li, Xiaoli, Cen, Yanyan, Cai, Yongqing, Liu, Tao, Liu, Huan, Cao, Guanqun, Liu, Dan, Li, Bin, Peng, Wei, Zou, Jintao, Pang, Xueli, Zheng, Jiang, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890034/
https://www.ncbi.nlm.nih.gov/pubmed/27251306
http://dx.doi.org/10.1038/srep27104

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