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Viable offspring obtained from Prm1-deficient sperm in mice

Protamines are expressed in the spermatid nucleus and allow denser packaging of DNA compared with histones. Disruption of the coding sequence of one allele of either protamine 1 (Prm1) or Prm2 results in failure to produce offspring, although sperm with disrupted Prm1 or Prm2 alleles are produced. H...

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Detalles Bibliográficos
Autores principales:	Takeda, Naoki, Yoshinaga, Kazuya, Furushima, Kenryo, Takamune, Kazufumi, Li, Zhenghua, Abe, Shin-ichi, Aizawa, Shin-ichi, Yamamura, Ken-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890041/ https://www.ncbi.nlm.nih.gov/pubmed/27250771 http://dx.doi.org/10.1038/srep27409

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