Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation

Expression of the viral virulence protein PB1-F2 during infection has been linked to NLRP3 inflammasome complex activation in macrophages and induction of early inflammatory events enhancing immunopathology during influenza disease. We sought to determine whether PB1-F2-specific NLRP3 inflammasome a...

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Detalles Bibliográficos
Autores principales: Lee, Patricia (Hoi Yee), Bird, Nicola, MacKenzie-Kludas, Charley, Mansell, Ashley, Kedzierska, Katherine, Brown, Lorena, McAuley, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890051/
https://www.ncbi.nlm.nih.gov/pubmed/26667784
http://dx.doi.org/10.1038/icb.2015.115

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