Apoptosis-mediated endothelial toxicity but not direct calcification or functional changes in anti-calcification proteins defines pathogenic effects of calcium phosphate bions

Calcium phosphate bions (CPB) are biomimetic mineralo-organic nanoparticles which represent a physiological mechanism regulating the function, transport and disposal of calcium and phosphorus in the human body. We hypothesised that CPB may be pathogenic entities and even a cause of cardiovascular ca...

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Detalles Bibliográficos
Autores principales: Kutikhin, Anton G., Velikanova, Elena A., Mukhamadiyarov, Rinat A., Glushkova, Tatiana V., Borisov, Vadim V., Matveeva, Vera G., Antonova, Larisa V., Filip’ev, Dmitriy E., Golovkin, Alexey S., Shishkova, Daria K., Burago, Andrey Yu., Frolov, Alexey V., Dolgov, Viktor Yu., Efimova, Olga S., Popova, Anna N., Malysheva, Valentina Yu., Vladimirov, Alexandr A., Sozinov, Sergey A., Ismagilov, Zinfer R., Russakov, Dmitriy M., Lomzov, Alexander A., Pyshnyi, Dmitriy V., Gutakovsky, Anton K., Zhivodkov, Yuriy A., Demidov, Evgeniy A., Peltek, Sergey E., Dolganyuk, Viatcheslav F., Babich, Olga O., Grigoriev, Evgeniy V., Brusina, Elena B., Barbarash, Olga L., Yuzhalin, Arseniy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890115/
https://www.ncbi.nlm.nih.gov/pubmed/27251104
http://dx.doi.org/10.1038/srep27255

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