Withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation

Activation of inflammatory pathways via reactive oxygen species (ROS) by free fatty acids (FFA) in obesity gives rise to insulin resistance and endothelial dysfunction. Withaferin A (WA), possesses both antioxidant and anti-inflammatory properties and therefore would be a good strategy to suppress p...

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Detalles Bibliográficos
Autores principales: Batumalaie, Kalaivani, Amin, Muhammad Arif, Murugan, Dharmani Devi, Sattar, Munavvar Zubaid Abdul, Abdullah, Nor Azizan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890118/
https://www.ncbi.nlm.nih.gov/pubmed/27250532
http://dx.doi.org/10.1038/srep27236

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