Annexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function

The phospholipid- and Ca(2+)-binding protein annexin A5 (ANXA5) is the most abundant membrane-associated protein of ~P23 mouse vestibular hair bundles, the inner ear’s sensory organelle. Using quantitative mass spectrometry, we estimated that ANXA5 accounts for ~15,000 copies per stereocilium, or ~2...

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Detalles Bibliográficos
Autores principales: Krey, Jocelyn F., Drummond, Meghan, Foster, Sarah, Porsov, Edward, Vijayakumar, Sarath, Choi, Dongseok, Friderici, Karen, Jones, Sherri M., Nuttall, Alfred L., Barr-Gillespie, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890179/
https://www.ncbi.nlm.nih.gov/pubmed/27251877
http://dx.doi.org/10.1038/srep27221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890179/
https://www.ncbi.nlm.nih.gov/pubmed/27251877
http://dx.doi.org/10.1038/srep27221

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