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Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype

BACKGROUND: Notochordal cell conditioned medium (NCCM) derived from non-chondrodystrophic dogs has pro-anabolic and anti-catabolic effects upon nucleus pulposus (NP) cells. Here, for the first time, we assessed the ability of NCCM to influence the production of extracellular matrix and inflammatory...

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Detalles Bibliográficos
Autores principales: Müller, Sebastian, Acevedo, Lina, Wang, Xiaomei, Karim, M. Zia, Matta, Ajay, Mehrkens, Arne, Schaeren, Stefan, Feliciano, Sandra, Jakob, Marcel, Martin, Ivan, Barbero, Andrea, Erwin, W. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890286/
https://www.ncbi.nlm.nih.gov/pubmed/27255741
http://dx.doi.org/10.1186/s13075-016-1026-x

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