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Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype
BACKGROUND: Notochordal cell conditioned medium (NCCM) derived from non-chondrodystrophic dogs has pro-anabolic and anti-catabolic effects upon nucleus pulposus (NP) cells. Here, for the first time, we assessed the ability of NCCM to influence the production of extracellular matrix and inflammatory...
Autores principales: | Müller, Sebastian, Acevedo, Lina, Wang, Xiaomei, Karim, M. Zia, Matta, Ajay, Mehrkens, Arne, Schaeren, Stefan, Feliciano, Sandra, Jakob, Marcel, Martin, Ivan, Barbero, Andrea, Erwin, W. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890286/ https://www.ncbi.nlm.nih.gov/pubmed/27255741 http://dx.doi.org/10.1186/s13075-016-1026-x |
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