DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways

Astrocyte elevated gene-1 (AEG-1) has been explored as a novel target for human glioma therapy, thus reflecting its potential contribution to gliomagenesis. In the present study, we investigated the effect of DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, on cell growth and invasion...

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Detalles Bibliográficos
Autores principales: Zou, Meijuan, Duan, Yongtao, Wang, Pengfei, Gao, Rui, Chen, Xuguan, Ou, Yingwei, Liang, Mingxing, Wang, Zhongchang, Yuan, Yi, Wang, Li, Zhu, Hailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890319/
https://www.ncbi.nlm.nih.gov/pubmed/27251589
http://dx.doi.org/10.1038/srep27331

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