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P2X6 Knockout Mice Exhibit Normal Electrolyte Homeostasis

ATP-mediated signaling is an important regulator of electrolyte transport in the kidney. The purinergic cation channel P2X6 has been previously localized to the distal convoluted tubule (DCT), a nephron segment important for Mg(2+) and Na(+) reabsorption, but its role in ion transport remains unknow...

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Detalles Bibliográficos
Autores principales: de Baaij, Jeroen H. F., Kompatscher, Andreas, Viering, Daan H. H. M., Bos, Caro, Bindels, René J. M., Hoenderop, Joost G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890750/
https://www.ncbi.nlm.nih.gov/pubmed/27254077
http://dx.doi.org/10.1371/journal.pone.0156803