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Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis

BACKGROUND: Triggering receptor expressed on myeloid cells (TREM) -1 and TREM-2 are key regulators of the inflammatory response that are involved in the clearance of invading pathogens. Melioidosis, caused by the "Tier 1" biothreat agent Burkholderia pseudomallei, is a common form of commu...

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Detalles Bibliográficos
Autores principales:	Weehuizen, Tassili A. F., Hommes, Tijmen J., Lankelma, Jacqueline M., de Jong, Hanna K., Roelofs, Joris. J.T.H., de Vos, Alex F., Colonna, Marco, van der Poll, Tom, Wiersinga, W. Joost
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890812/ https://www.ncbi.nlm.nih.gov/pubmed/27253382 http://dx.doi.org/10.1371/journal.pntd.0004747

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