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The Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality Control
The Not4 RING E3 ligase is a subunit of the evolutionarily conserved Ccr4-Not complex. Originally identified in yeast by mutations that increase transcription, it was subsequently defined as an ubiquitin ligase. Substrates for this ligase were characterized in yeast and in metazoans. Interestingly,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890865/ https://www.ncbi.nlm.nih.gov/pubmed/27335678 http://dx.doi.org/10.1155/2013/548359 |