Pathophysiological Significance of Hepatic Apoptosis

Apoptosis is a classical pathological feature in liver diseases caused by various etiological factors such as drugs, viruses, alcohol, and cholestasis. Hepatic apoptosis and its deleterious effects exacerbate liver function as well as involvement in fibrosis/cirrhosis and carcinogenesis. An imbalanc...

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Detalles Bibliográficos
Autores principales: Wang, Kewei, Lin, Bingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890876/
https://www.ncbi.nlm.nih.gov/pubmed/27335822
http://dx.doi.org/10.1155/2013/740149
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author Wang, Kewei
Lin, Bingliang
author_facet Wang, Kewei
Lin, Bingliang
author_sort Wang, Kewei
collection PubMed
description Apoptosis is a classical pathological feature in liver diseases caused by various etiological factors such as drugs, viruses, alcohol, and cholestasis. Hepatic apoptosis and its deleterious effects exacerbate liver function as well as involvement in fibrosis/cirrhosis and carcinogenesis. An imbalance between apoptotic and antiapoptotic capabilities is a prominent characteristic of liver injury. The regulation of apoptosis and antiapoptosis can be a pivotal step in the treatment of liver diseases.
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spelling pubmed-48908762016-06-22 Pathophysiological Significance of Hepatic Apoptosis Wang, Kewei Lin, Bingliang ISRN Hepatol Review Article Apoptosis is a classical pathological feature in liver diseases caused by various etiological factors such as drugs, viruses, alcohol, and cholestasis. Hepatic apoptosis and its deleterious effects exacerbate liver function as well as involvement in fibrosis/cirrhosis and carcinogenesis. An imbalance between apoptotic and antiapoptotic capabilities is a prominent characteristic of liver injury. The regulation of apoptosis and antiapoptosis can be a pivotal step in the treatment of liver diseases. Hindawi Publishing Corporation 2012-12-30 /pmc/articles/PMC4890876/ /pubmed/27335822 http://dx.doi.org/10.1155/2013/740149 Text en Copyright © 2013 K. Wang and B. Lin. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wang, Kewei
Lin, Bingliang
Pathophysiological Significance of Hepatic Apoptosis
title Pathophysiological Significance of Hepatic Apoptosis
title_full Pathophysiological Significance of Hepatic Apoptosis
title_fullStr Pathophysiological Significance of Hepatic Apoptosis
title_full_unstemmed Pathophysiological Significance of Hepatic Apoptosis
title_short Pathophysiological Significance of Hepatic Apoptosis
title_sort pathophysiological significance of hepatic apoptosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890876/
https://www.ncbi.nlm.nih.gov/pubmed/27335822
http://dx.doi.org/10.1155/2013/740149
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