Cargando…
High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria
[Image: see text] In order to identify the most attractive starting points for drugs that can be used to prevent malaria, a diverse chemical space comprising tens of thousands to millions of small molecules may need to be examined. Achieving this throughput necessitates the development of efficient...
Autores principales: | Swann, Justine, Corey, Victoria, Scherer, Christina A., Kato, Nobutaka, Comer, Eamon, Maetani, Micah, Antonova-Koch, Yevgeniya, Reimer, Christin, Gagaring, Kerstin, Ibanez, Maureen, Plouffe, David, Zeeman, Anne-Marie, Kocken, Clemens H. M., McNamara, Case W., Schreiber, Stuart L., Campo, Brice, Winzeler, Elizabeth A., Meister, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890880/ https://www.ncbi.nlm.nih.gov/pubmed/27275010 http://dx.doi.org/10.1021/acsinfecdis.5b00143 |
Ejemplares similares
-
Synthesis
of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled
by Stereospecific, Directed C(sp(3))–H Arylation
por: Maetani, Micah, et al.
Publicado: (2017) -
Probing the Open
Global Health Chemical Diversity
Library for Multistage-Active Starting Points for Next-Generation
Antimalarials
por: Abraham, Matthew, et al.
Publicado: (2020) -
Mutations in the P-Type Cation-Transporter
ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone
Antimalarials
por: Flannery, Erika L., et al.
Publicado: (2014) -
KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro
por: Zeeman, Anne-Marie, et al.
Publicado: (2014) -
High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission
por: Plouffe, David M., et al.
Publicado: (2016)