Regulation of GLUT4 and Insulin-Dependent Glucose Flux

GLUT4 has long been known to be an insulin responsive glucose transporter. Regulation of GLUT4 has been a major focus of research on the cause and prevention of type 2 diabetes. Understanding how insulin signaling alters the intracellular trafficking of GLUT4 as well as understanding the fate of glu...

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Detalles Bibliográficos
Autor principal: Olson, Ann Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890881/
https://www.ncbi.nlm.nih.gov/pubmed/27335671
http://dx.doi.org/10.5402/2012/856987
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author Olson, Ann Louise
author_facet Olson, Ann Louise
author_sort Olson, Ann Louise
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description GLUT4 has long been known to be an insulin responsive glucose transporter. Regulation of GLUT4 has been a major focus of research on the cause and prevention of type 2 diabetes. Understanding how insulin signaling alters the intracellular trafficking of GLUT4 as well as understanding the fate of glucose transported into the cell by GLUT4 will be critically important for seeking solutions to the current rise in diabetes and metabolic disease.
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spelling pubmed-48908812016-06-22 Regulation of GLUT4 and Insulin-Dependent Glucose Flux Olson, Ann Louise ISRN Mol Biol Review Article GLUT4 has long been known to be an insulin responsive glucose transporter. Regulation of GLUT4 has been a major focus of research on the cause and prevention of type 2 diabetes. Understanding how insulin signaling alters the intracellular trafficking of GLUT4 as well as understanding the fate of glucose transported into the cell by GLUT4 will be critically important for seeking solutions to the current rise in diabetes and metabolic disease. International Scholarly Research Network 2012-10-17 /pmc/articles/PMC4890881/ /pubmed/27335671 http://dx.doi.org/10.5402/2012/856987 Text en Copyright © 2012 Ann Louise Olson. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Olson, Ann Louise
Regulation of GLUT4 and Insulin-Dependent Glucose Flux
title Regulation of GLUT4 and Insulin-Dependent Glucose Flux
title_full Regulation of GLUT4 and Insulin-Dependent Glucose Flux
title_fullStr Regulation of GLUT4 and Insulin-Dependent Glucose Flux
title_full_unstemmed Regulation of GLUT4 and Insulin-Dependent Glucose Flux
title_short Regulation of GLUT4 and Insulin-Dependent Glucose Flux
title_sort regulation of glut4 and insulin-dependent glucose flux
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890881/
https://www.ncbi.nlm.nih.gov/pubmed/27335671
http://dx.doi.org/10.5402/2012/856987
work_keys_str_mv AT olsonannlouise regulationofglut4andinsulindependentglucoseflux

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