Cargando…
TGF-β/Smad3 signalling regulates the transition of bone marrow-derived macrophages into myofibroblasts during tissue fibrosis
Myofibroblasts are a main cell-type of collagen-producing cells during tissue fibrosis, but their origins remains controversial. While bone marrow-derived myofibroblasts in renal fibrosis has been reported, the cell origin and mechanisms regulating their transition into myofibroblasts remain undefin...
Autores principales: | Wang, Shuang, Meng, Xiao-Ming, Ng, Yee-Yung, Ma, Frank Y., Zhou, Shuang, Zhang, Yang, Yang, Chen, Huang, Xiao-Ru, Xiao, Jun, Wang, Ying-Ying, Ka, Shuk-Man, Tang, Yong-Jiang, Chung, Arthur C.K., To, Ka-Fai, Nikolic-Paterson, David J., Lan, Hui-Yao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891006/ https://www.ncbi.nlm.nih.gov/pubmed/26684242 http://dx.doi.org/10.18632/oncotarget.6604 |
Ejemplares similares
-
Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2016) -
Smad3 Promotes Cancer‐Associated Fibroblasts Generation via Macrophage–Myofibroblast Transition
por: Tang, Philip Chiu‐Tsun, et al.
Publicado: (2021) -
Smad4-mediated TGF-β signaling in tumorigenesis
por: Yang, Guan, et al.
Publicado: (2010) -
Activation of Wnt/β‐catenin signalling is required for TGF‐β/Smad2/3 signalling during myofibroblast proliferation
por: Xu, Liang, et al.
Publicado: (2017) -
Mesenchymal stem cells reversibly de-differentiate myofibroblasts to fibroblast-like cells by inhibiting the TGF-β-SMAD2/3 pathway
por: Xu, Ruohao, et al.
Publicado: (2023)