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TGF-β/Smad3 signalling regulates the transition of bone marrow-derived macrophages into myofibroblasts during tissue fibrosis

Myofibroblasts are a main cell-type of collagen-producing cells during tissue fibrosis, but their origins remains controversial. While bone marrow-derived myofibroblasts in renal fibrosis has been reported, the cell origin and mechanisms regulating their transition into myofibroblasts remain undefin...

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Detalles Bibliográficos
Autores principales: Wang, Shuang, Meng, Xiao-Ming, Ng, Yee-Yung, Ma, Frank Y., Zhou, Shuang, Zhang, Yang, Yang, Chen, Huang, Xiao-Ru, Xiao, Jun, Wang, Ying-Ying, Ka, Shuk-Man, Tang, Yong-Jiang, Chung, Arthur C.K., To, Ka-Fai, Nikolic-Paterson, David J., Lan, Hui-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891006/
https://www.ncbi.nlm.nih.gov/pubmed/26684242
http://dx.doi.org/10.18632/oncotarget.6604

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