Cargando…

Generation of functional hepatocytes from human spermatogonial stem cells

To generate functional human hepatocytes from stem cells and/or extra-hepatic tissues could provide an important source of cells for treating liver diseases. Spermatogonial stem cells (SSCs) have an unlimited plasticity since they can dedifferentiate and transdifferentiate to other cell lineages. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zheng, Sun, Min, Yuan, Qingqing, Niu, Minghui, Yao, Chencheng, Hou, Jingmei, Wang, Hong, Wen, Liping, Liu, Yun, Li, Zheng, He, Zuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891011/ https://www.ncbi.nlm.nih.gov/pubmed/26840458 http://dx.doi.org/10.18632/oncotarget.7092

Ejemplares similares

Transdifferentiation of human male germline stem cells to hepatocytes in vivo via the transplantation under renal capsules
por: Chen, Zheng, et al.
Publicado: (2017)

MiRNA-133b promotes the proliferation of human Sertoli cells through targeting GLI3
por: Yao, Chencheng, et al.
Publicado: (2016)

Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system
por: Sun, Min, et al.
Publicado: (2018)

Derivation and propagation of spermatogonial stem cells from human pluripotent cells
por: Xu, Huiming, et al.
Publicado: (2020)

PAK1 Promotes the Proliferation and Inhibits Apoptosis of Human Spermatogonial Stem Cells via PDK1/KDR/ZNF367 and ERK1/2 and AKT Pathways
por: Fu, Hongyong, et al.
Publicado: (2018)

Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase
por: Wen, Liping, et al.
Publicado: (2017)

Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation
por: Tian, Ruhui, et al.
Publicado: (2019)

MiR-663a Stimulates Proliferation and Suppresses Early Apoptosis of Human Spermatogonial Stem Cells by Targeting NFIX and Regulating Cell Cycle
por: Zhou, Fan, et al.
Publicado: (2018)

BMP6 Regulates Proliferation and Apoptosis of Human Sertoli Cells Via Smad2/3 and Cyclin D1 Pathway and DACH1 and TFAP2A Activation
por: Wang, Hong, et al.
Publicado: (2017)

FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells
por: Qiu, Qianqian, et al.
Publicado: (2019)

Distinct Expression Profiles and Novel Targets of MicroRNAs in Human Spermatogonia, Pachytene Spermatocytes, and Round Spermatids between OA Patients and NOA Patients
por: Yao, Chencheng, et al.
Publicado: (2017)

Characterization, isolation, and culture of spermatogonial stem cells in Macaca fascicularis
por: Mao, Guo-Ping, et al.
Publicado: (2021)

Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation
por: Hou, Jingmei, et al.
Publicado: (2015)

Corrigendum: Establishment and Characterization of Human Germline Stem Cell Line with Unlimited Proliferation Potentials and no Tumor Formation
por: Hou, Jingmei, et al.
Publicado: (2017)

Fractionation of human spermatogenic cells using STA-PUT gravity sedimentation and their miRNA profiling
por: Liu, Yun, et al.
Publicado: (2015)

Generation of Haploid Spermatids with Fertilization and Development Capacity from Human Spermatogonial Stem Cells of Cryptorchid Patients
por: Yang, Shi, et al.
Publicado: (2014)

Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation
por: Guo, Ying, et al.
Publicado: (2015)

miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7
por: Zhou, Fan, et al.
Publicado: (2020)

AB182. Efficient generation of haploid spermatids with Fertilization and development capacity from human spermatogonial stem cells of cryptorchid patients
por: Yang, Shi, et al.
Publicado: (2014)

miRNA-31-5p Mediates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells via Targeting JAZF1 and Cyclin A2
por: Fu, Hongyong, et al.
Publicado: (2018)

Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice
por: Wang, Hong, et al.
Publicado: (2018)

Direct transdifferentiation of spermatogonial stem cells to morphological, phenotypic and functional hepatocyte-like cells via the ERK1/2 and Smad2/3 signaling pathways and the inactivation of cyclin A, cyclin B and cyclin E
por: Zhang, Zhenzhen, et al.
Publicado: (2013)

Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
por: Nóbrega, Rafael Henrique, et al.
Publicado: (2010)

Alpha-tocopherol enhances spermatogonial stem cell proliferation and restores mouse spermatogenesis by up-regulating BMI1
por: Peng, Mei, et al.
Publicado: (2023)

Direct reprogramming of human Sertoli cells into male germline stem cells with the self-renewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE genes
por: Zhang, Wenhui, et al.
Publicado: (2021)

Spermatogonial stem cells, infertility and testicular cancer
por: Singh, Shree Ram, et al.
Publicado: (2011)

TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL
por: Zhou, Dai, et al.
Publicado: (2021)

Alteration of protein prenylation promotes spermatogonial differentiation and exhausts spermatogonial stem cells in newborn mice
por: Diao, Fan, et al.
Publicado: (2016)

Plasticity of spermatogonial stem cells
por: Cooke, Paul S, et al.
Publicado: (2015)

GPx3 knockdown inhibits the proliferation and DNA synthesis and enhances the early apoptosis of human spermatogonial stem cells via mediating CXCL10 and cyclin B1
por: Wu, Si, et al.
Publicado: (2023)

OIP5 Interacts with NCK2 to Mediate Human Spermatogonial Stem Cell Self-Renewal and Apoptosis through Cell Cyclins and Cycle Progression and Its Abnormality Is Correlated with Male Infertility
por: Cui, Yinghong, et al.
Publicado: (2023)

Lovastatin promotes the self-renewal of murine and primate spermatogonial stem cells
por: Li, Chaohui, et al.
Publicado: (2023)

MAP4K4/JNK Signaling Pathway Stimulates Proliferation and Suppresses Apoptosis of Human Spermatogonial Stem Cells and Lower Level of MAP4K4 Is Associated with Male Infertility
por: Wan, Cailin, et al.
Publicado: (2022)

Generation of Mouse Spermatogonial Stem-Cell-Colonies in A Non-Adherent Culture
por: Azizi, Hossein, et al.
Publicado: (2017)

Establishment of cell lines with porcine spermatogonial stem cell properties
por: Zheng, Yi, et al.
Publicado: (2020)

Spermatogonial stem cell regulation and spermatogenesis
por: Phillips, Bart T., et al.
Publicado: (2010)

Spermatogonial stem cells: progress and prospects
por: Komeya, Mitsuru, et al.
Publicado: (2015)

Characterization of Spermatogonial Stem Cells Lacking Intercellular Bridges and Genetic Replacement of a Mutation in Spermatogonial Stem Cells
por: Iwamori, Naoki, et al.
Publicado: (2012)

Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes
por: Yang, Hao, et al.
Publicado: (2019)

Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats
por: TIPTANAVATTANA, Narong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_nl1stni945toahihsuasn4p58j