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Chromosomal anomalies at 1q, 3, 16q, and mutations of SIX1 and DROSHA genes underlie Wilms tumor recurrences

Approximately half of children suffering from recurrent Wilms tumor (WT) develop resistance to salvage therapies. Hence the importance to disclose events driving tumor progression/recurrence. Future therapeutic trials, conducted in the setting of relapsing patients, will need to prioritize targets p...

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Detalles Bibliográficos
Autores principales: Spreafico, Filippo, Ciceri, Sara, Gamba, Beatrice, Torri, Federica, Terenziani, Monica, Collini, Paola, Macciardi, Fabio, Radice, Paolo, Perotti, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891013/
https://www.ncbi.nlm.nih.gov/pubmed/26802027
http://dx.doi.org/10.18632/oncotarget.6950