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Chromosomal anomalies at 1q, 3, 16q, and mutations of SIX1 and DROSHA genes underlie Wilms tumor recurrences
Approximately half of children suffering from recurrent Wilms tumor (WT) develop resistance to salvage therapies. Hence the importance to disclose events driving tumor progression/recurrence. Future therapeutic trials, conducted in the setting of relapsing patients, will need to prioritize targets p...
Autores principales: | Spreafico, Filippo, Ciceri, Sara, Gamba, Beatrice, Torri, Federica, Terenziani, Monica, Collini, Paola, Macciardi, Fabio, Radice, Paolo, Perotti, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891013/ https://www.ncbi.nlm.nih.gov/pubmed/26802027 http://dx.doi.org/10.18632/oncotarget.6950 |
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