Tristetraprolin suppresses the EMT through the down-regulation of Twist1 and Snail1 in cancer cells

Inhibition of epithelial-mesenchymal transition (EMT)-inducing transcription factors Twist and Snail prevents tumor metastasis but enhances metastatic growth. Here, we report an unexpected role of a tumor suppressor tristetraprolin (TTP) in inhibiting Twist and Snail without enhancing cellular proli...

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Detalles Bibliográficos
Autores principales: Yoon, Nal Ae, Jo, Hyun Gun, Lee, Unn Hwa, Park, Ji Hye, Yoon, Ji Eun, Ryu, Jinhyun, Kang, Sang Soo, Min, Young Joo, Ju, Seong-A, Seo, Eun Hui, Huh, In Young, Lee, Byung Ju, Park, Jeong Woo, Cho, Wha Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891015/
https://www.ncbi.nlm.nih.gov/pubmed/26840564
http://dx.doi.org/10.18632/oncotarget.7094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891015/
https://www.ncbi.nlm.nih.gov/pubmed/26840564
http://dx.doi.org/10.18632/oncotarget.7094

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