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Tristetraprolin suppresses the EMT through the down-regulation of Twist1 and Snail1 in cancer cells
Inhibition of epithelial-mesenchymal transition (EMT)-inducing transcription factors Twist and Snail prevents tumor metastasis but enhances metastatic growth. Here, we report an unexpected role of a tumor suppressor tristetraprolin (TTP) in inhibiting Twist and Snail without enhancing cellular proli...
Autores principales: | Yoon, Nal Ae, Jo, Hyun Gun, Lee, Unn Hwa, Park, Ji Hye, Yoon, Ji Eun, Ryu, Jinhyun, Kang, Sang Soo, Min, Young Joo, Ju, Seong-A, Seo, Eun Hui, Huh, In Young, Lee, Byung Ju, Park, Jeong Woo, Cho, Wha Ja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891015/ https://www.ncbi.nlm.nih.gov/pubmed/26840564 http://dx.doi.org/10.18632/oncotarget.7094 |
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