Delivery of improved oncolytic adenoviruses by mesenchymal stromal cells for elimination of tumorigenic pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive malignancies and has poor therapeutic options. We evaluated improved oncolytic adenoviruses (OAds), in which the adenoviral gene E1B19K was deleted or a TRAIL transgene was inserted. Bone marrow mesenchymal stromal cells (MSCs) ser...

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Detalles Bibliográficos
Autores principales: Kaczorowski, Adam, Hammer, Katharina, Liu, Li, Villhauer, Sabine, Nwaeburu, Clifford, Fan, Pei, Zhao, Zhefu, Gladkich, Jury, Groß, Wolfgang, Nettelbeck, Dirk M., Herr, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891025/
https://www.ncbi.nlm.nih.gov/pubmed/26824985
http://dx.doi.org/10.18632/oncotarget.7031

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