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Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

Mutations in splicing factor (SF) genes are frequently detected in myelodysplastic syndrome, but the prognostic relevance of these genes mutations in acute myeloid leukemia (AML) remains unclear. In this study, we investigated mutations of three SF genes, SF3B1, U2AF1 and SRSF2, by Sanger sequencing...

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Detalles Bibliográficos
Autores principales:	Hou, Hsin-An, Liu, Chieh-Yu, Kuo, Yuan-Yeh, Chou, Wen-Chien, Tsai, Cheng-Hong, Lin, Chien-Chin, Lin, Liang-In, Tseng, Mei-Hsuan, Chiang, Ying-Chieh, Liu, Ming-Chih, Liu, Chia-Wen, Tang, Jih-Luh, Yao, Ming, Li, Chi-Cheng, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Chen, Chien-Yuan, Lin, Chien-Ting, Wu, Shang-Ju, Tsay, Woei, Tien, Hwei-Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891028/ https://www.ncbi.nlm.nih.gov/pubmed/26812887 http://dx.doi.org/10.18632/oncotarget.7000

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