MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes

Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). In cancer, this process is frequently altered by deregulated expre...

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Detalles Bibliográficos
Autores principales: Soriano, Aroa, París-Coderch, Laia, Jubierre, Luz, Martínez, Alba, Zhou, Xiangyu, Piskareva, Olga, Bray, Isabella, Vidal, Isaac, Almazán-Moga, Ana, Molist, Carla, Roma, Josep, Bayascas, José R., Casanovas, Oriol, Stallings, Raymond L., de Toledo, José Sánchez, Gallego, Soledad, Segura, Miguel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891039/
https://www.ncbi.nlm.nih.gov/pubmed/26824183
http://dx.doi.org/10.18632/oncotarget.7005

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