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Fatty acid activated PPARγ promotes tumorigenicity of prostate cancer cells by up regulating VEGF via PPAR responsive elements of the promoter
In previous work, it is suggested that the excessive amount of fatty acids transported by FABP5 may facilitate the malignant progression of prostate cancer cells through a FABP5-PPARγ-VEGF signal transduction axis to increase angiogenesis. To further functionally characterise the FABP5-PPARγ-VEGF si...
Autores principales: | Forootan, Farzad S., Forootan, Shiva S., Gou, Xiaojun, Yang, Jin, Liu, Bichong, Chen, Danqing, Fayi, Majed Saad Al, Al-Jameel, Waseem, Rudland, Philip S., Hussain, Syed A., Ke, Youqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891043/ https://www.ncbi.nlm.nih.gov/pubmed/26814431 http://dx.doi.org/10.18632/oncotarget.6975 |
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