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Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells

The therapeutic potential of RNA interference (RNAi) has been limited by inefficient delivery of short interfering RNA (siRNA). Tumor-specific recognition can be effectively achieved by antibodies directed against highly expressed cancer cell surface receptors. We investigated the utility of linking...

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Detalles Bibliográficos
Autores principales:	Palanca-Wessels, Maria C., Booth, Garrett C., Convertine, Anthony J., Lundy, Brittany B., Berguig, Geoffrey Y., Press, Michael F., Stayton, Patrick S., Press, Oliver W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891060/ https://www.ncbi.nlm.nih.gov/pubmed/26840082 http://dx.doi.org/10.18632/oncotarget.7076

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