Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and in vivo study

Cancer stem cell theory indicates cancer stem cells are the key to promote tumor invasion and metastasis. Studies showed that BMI-1 could promote self-renew, differentiation and tumor formation of CSCs and invasion/metastasis of human cancer. However, whether BMI-1 could regulate invasion and metast...

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Detalles Bibliográficos
Autores principales: Wang, Min-Cong, Jiao, Min, Wu, Tao, Jing, Li, Cui, Jie, Guo, Hui, Tian, Tao, Ruan, Zhi-ping, Wei, Yong-Chang, Jiang, Li-Li, Sun, Hai-Feng, Huang, Lan-Xuan, Nan, Ke-Jun, Li, Chun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891062/
https://www.ncbi.nlm.nih.gov/pubmed/26840020
http://dx.doi.org/10.18632/oncotarget.7078

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