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GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells

Growth differentiation factor 15 (GDF15) is an emerging biomarker of cardiovascular risk and disease. Microarray analyses revealed that GDF15 levels were increased during cellular senescence induced by ionizing radiation (IR) in human aortic endothelial cells (HAECs). However, the role of GDF15 in H...

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Detalles Bibliográficos
Autores principales:	Park, Hyejin, Kim, Chun-Ho, Jeong, Jae-Hoon, Park, Myungjin, Kim, Kwang Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891072/ https://www.ncbi.nlm.nih.gov/pubmed/26909594 http://dx.doi.org/10.18632/oncotarget.7457

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