Guanylate binding protein-1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro

Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults. Epidermal growth factor receptor (EGFR) is frequently amplified and mutated in GBM. We previously reported that Guanylate binding protein-1 (GBP1) is a novel transcriptional target gene of EGFR and plays a rol...

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Detalles Bibliográficos
Autores principales: Lan, Qing, Wang, Aidong, Cheng, Yanwei, Mukasa, Akitaki, Ma, Jiawei, Hong, Lei, Yu, Shuye, Sun, Lili, Huang, Qiang, Purow, Benjamin, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891076/
https://www.ncbi.nlm.nih.gov/pubmed/26848767
http://dx.doi.org/10.18632/oncotarget.7109

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