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Genetic evaluation of BRCA1-A complex genes with triple-negative breast cancer susceptibility in Chinese women

BACKGROUND: The tumor suppressor BRCA1 plays a pivotal role in maintaining genomic stability and tumor suppression. The BRCA1-A complex is required for recruitment of BRCA1 to DNA damage sites, DNA repair and cell cycle checkpoint control. Since germline mutations of BRCA1 often lead to breast tumor...

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Detalles Bibliográficos
Autores principales: Ling, Hong, Li, Shan, Wu, Yang, Zheng, Yi-Zi, Qiao, Feng, Yao, Ling, Cao, Zhi-Gang, Ye, Fu-Gui, Wu, Jiong, Hu, Xin, Wang, Bin, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891082/
https://www.ncbi.nlm.nih.gov/pubmed/26848770
http://dx.doi.org/10.18632/oncotarget.7112

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