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Identification of drugs that restore primary cilium expression in cancer cells

The development of cancer is often accompanied by a loss of the primary cilium, a microtubule-based cellular protrusion that functions as a cellular antenna and that puts a break on cell proliferation. Hence, restoration of the primary cilium in cancer cells may represent a novel promising approach...

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Detalles Bibliográficos
Autores principales: Khan, Niamat Ali, Willemarck, Nicolas, Talebi, Ali, Marchand, Arnaud, Binda, Maria Mercedes, Dehairs, Jonas, Rueda-Rincon, Natalia, Daniels, Veerle W., Bagadi, Muralidhararao, Raj, Deepak Balaji Thimiri Govinda, Vanderhoydonc, Frank, Munck, Sebastian, Chaltin, Patrick, Swinnen, Johannes V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891097/
https://www.ncbi.nlm.nih.gov/pubmed/26862738
http://dx.doi.org/10.18632/oncotarget.7198