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Oncogenic K-ras confers SAHA resistance by up-regulating HDAC6 and c-myc expression

Histone deacetylase inhibitors (HDIs) represent a new class of anticancer drugs. Suberoylanilide hydroxamic acid (SAHA), the first HDI approved for the treatment of cutaneous T cell lymphoma (CTCL), is currently being tested in clinical trials for other cancers. However, SAHA has been ineffective ag...

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Detalles Bibliográficos
Autores principales:	Wang, Qun, Tan, Rong, Zhu, Xin, Zhang, Yi, Tan, Zhiping, Su, Bing, Li, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891104/ https://www.ncbi.nlm.nih.gov/pubmed/26848526 http://dx.doi.org/10.18632/oncotarget.7134

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