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Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate
In this study the detailed characteristic of the anti-cancer agent 3-bromopyruvate (3-BP) activity in the yeast Saccharomyces cerevisiae model is described, with the emphasis on its influence on energetic metabolism of the cell. It shows that 3-BP toxicity in yeast is strain-dependent and influenced...
Autores principales: | Lis, Paweł, Jurkiewicz, Paweł, Cal-Bąkowska, Magdalena, Ko, Young H., Pedersen, Peter L., Goffeau, Andre, Ułaszewski, Stanisław |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891110/ https://www.ncbi.nlm.nih.gov/pubmed/26862728 http://dx.doi.org/10.18632/oncotarget.7174 |
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