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Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling
Wnt signaling pathway is aberrantly activated in a variety of cancers, especially in colorectal cancer and small molecule antagonists of Wnt/β-catenin signaling are attractive candidates for developing effective therapeutics. In the present study, we identified Bisleuconothine A, a bisindole alkaloi...
Autores principales: | Kong, Ling-Mei, Feng, Tao, Wang, Yuan-Yuan, Li, Xing-Yao, Ye, Zhen-Nan, An, Tao, Qing, Chen, Luo, Xiao-Dong, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891114/ https://www.ncbi.nlm.nih.gov/pubmed/26862734 http://dx.doi.org/10.18632/oncotarget.7190 |
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