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miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2

MicroRNA array analysis revealed that miR-217 expression was decreased in anti-cancer drug-resistant Malme3M(R) cancer cells. CAGE, a cancer/testis antigen, was predicted as a target of miR-217. Luciferase activity and ChIP assays revealed a negative feedback relationship between CAGE and miR-217. m...

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Detalles Bibliográficos
Autores principales:	Kim, Youngmi, Kim, Hyuna, Park, Deokbum, Han, Minho, Lee, Hansoo, Lee, Yun Sil, Choe, Jongseon, Kim, Young Myeong, Jeoung, Dooil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891121/ https://www.ncbi.nlm.nih.gov/pubmed/26863629 http://dx.doi.org/10.18632/oncotarget.7185

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