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Activation of the PD-1/PD-L1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis

The ability of tumor cells to avoid immune destruction (immune escape) as well as their acquired resistance to anti-cancer drugs constitute important barriers to the successful management of cancer. Interaction between the Programmed Death Ligand 1 (PD-L1) on the surface of tumor cells with the Prog...

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Detalles Bibliográficos
Autores principales: Black, Madison, Barsoum, Ivraym B., Truesdell, Peter, Cotechini, Tiziana, Macdonald-Goodfellow, Shannyn K., Petroff, Margaret, Siemens, D. Robert, Koti, Madhuri, Craig, Andrew W.B., Graham, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891140/
https://www.ncbi.nlm.nih.gov/pubmed/26859684
http://dx.doi.org/10.18632/oncotarget.7235

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