Cargando…

PHOX2B is a suppressor of neuroblastoma metastasis

Paired like homeobox 2B (PHOX2B) is a minimal residual disease (MRD) marker of neuroblastoma. The presence of MRD, also referred to as micro-metastases, is a powerful marker of poor prognosis in neuroblastoma. Lung metastasis is considered a terminal event in neuroblastoma. Lung micro-metastatic neu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Naftali, Osnat, Maman, Shelly, Meshel, Tsipi, Sagi-Assif, Orit, Ginat, Ravit, Witz, Isaac P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891146/ https://www.ncbi.nlm.nih.gov/pubmed/26840262 http://dx.doi.org/10.18632/oncotarget.7056

Ejemplares similares

Hexokinase 2 is a determinant of neuroblastoma metastasis
por: Edry Botzer, Liat, et al.
Publicado: (2016)

Cystatin C takes part in melanoma-microglia cross-talk: possible implications for brain metastasis
por: Moshe, Adi, et al.
Publicado: (2018)

Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression
por: Adir, Orit, et al.
Publicado: (2023)

ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis
por: Izraely, Sivan, et al.
Publicado: (2017)

CCR4 is a determinant of melanoma brain metastasis
por: Klein, Anat, et al.
Publicado: (2017)

The Challenge of Classifying Metastatic Cell Properties by Molecular Profiling Exemplified with Cutaneous Melanoma Cells and Their Cerebral Metastasis from Patient Derived Mouse Xenografts
por: Neuditschko, Benjamin, et al.
Publicado: (2020)

Inter-Tumor Heterogeneity—Melanomas Respond Differently to GM-CSF-Mediated Activation
por: Moshe, Adi, et al.
Publicado: (2020)

Regeneration Enhances Metastasis: A Novel Role for Neurovascular Signaling in Promoting Melanoma Brain Metastasis
por: Prakash, Roshini, et al.
Publicado: (2019)

The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway
por: Izraely, Sivan, et al.
Publicado: (2023)

The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells – a case of inter‐tumor heterogeneity
por: Izraely, Sivan, et al.
Publicado: (2020)

LY6S, a New IFN-Inducible Human Member of the Ly6a Subfamily Expressed by Spleen Cells and Associated with Inflammation and Viral Resistance
por: Shmerling, Moriya, et al.
Publicado: (2022)

Pleiotropic effect of common PHOX2B variants in Hirschsprung disease and neuroblastoma
por: Zhao, Jinglu, et al.
Publicado: (2019)

Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth
por: Zanni, Eleonora Di, et al.
Publicado: (2017)

Microenvironmental networks promote tumor heterogeneity and enrich for metastatic cancer stem-like cells in Luminal-A breast tumor cells
por: Weitzenfeld, Polina, et al.
Publicado: (2016)

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line
por: Di Lascio, Simona, et al.
Publicado: (2016)

Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models
por: Pei, Desheng, et al.
Publicado: (2013)

FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma
por: Li, Dan, et al.
Publicado: (2013)

Super-enhancer-associated TTC8 alters the nucleocytoplasmic distribution of PHOX2B and activates MAPK signaling in neuroblastoma
por: Zhuo, Ran, et al.
Publicado: (2022)

Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis
por: Ramos, Romela Irene, et al.
Publicado: (2020)

PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma
por: Bachetti, Tiziana, et al.
Publicado: (2010)

Contributions of PHOX2B in the Pathogenesis of Hirschsprung Disease
por: Fernández, Raquel María, et al.
Publicado: (2013)

Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico
por: Macías-Pérez, Martha Edith, et al.
Publicado: (2013)

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
Publicado: (1994)

CHL1 gene acts as a tumor suppressor in human neuroblastoma
por: Ognibene, Marzia, et al.
Publicado: (2018)

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma
por: Qiao, Jingbo, et al.
Publicado: (2019)

Exercise Training Attenuates Upregulation of p47(phox) and p67(phox) in Hearts of Diabetic Rats
por: Sharma, Neeru M., et al.
Publicado: (2016)

Pioglitazone Inhibits the Expressions of p22(phox) and p47(phox) in Rat Mesangial Cells In Vitro
por: Wang, Shan, et al.
Publicado: (2014)

The CASC15 long intergenic non-coding RNA locus is involved in melanoma progression and phenotype-switching
por: Lessard, Laurent, et al.
Publicado: (2015)

Epigenetic Changes of EGFR play an important role in BRAF inhibitor Resistant Cutaneous Melanomas
por: Wang, Jinhua, et al.
Publicado: (2014)

RT-qPCR for PHOX2B mRNA is a highly specific and sensitive method to assess neuroblastoma minimal residual disease in testicular tissue
por: Grèze, Victoria, et al.
Publicado: (2017)

Metastasis Suppressors and the Tumor Microenvironment
por: Bodenstine, Thomas M., et al.
Publicado: (2008)

Site‐specific metastasis: A cooperation between cancer cells and the metastatic microenvironment
por: Izraely, Sivan, et al.
Publicado: (2020)

Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast Cancer
por: Baram, Tamir, et al.
Publicado: (2022)

Transmembrane adaptor protein PAG1 is a novel tumor suppressor in neuroblastoma
por: Agarwal, Saurabh, et al.
Publicado: (2016)

The inflammatory cytokine TNFα cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells
por: Leibovich-Rivkin, Tal, et al.
Publicado: (2014)

Phox2b Influences the Development of a Caudal Dopaminergic Subset
por: Hoekstra, Elisa J., et al.
Publicado: (2012)

NeoPHOX – a structurally tunable ligand system for asymmetric catalysis
por: Padevět, Jaroslav, et al.
Publicado: (2016)

p22phox confers resistance to cisplatin, by blocking its entry into the nucleus
por: Hung, Chih-Chang, et al.
Publicado: (2015)

The correlation of p22(phox) and chemosensitivity in EGFR-TKI resistant lung adenocarcinoma
por: Kobayashi, Masayuki, et al.
Publicado: (2019)

The Tumor Microenvironment: The Making of a Paradigm
por: Witz, Isaac P.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_f13pv39i2lcq3q44i8f0je685n