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The expression of presenilin 1 enhances carcinogenesis and metastasis in gastric cancer

Presenilin 1 (PS-1, encoded by PSEN1) is a part of the gamma− (γ−) secretase complex. Mutations in PSEN1 cause the majority of cases of familial Alzheimer's disease (FAD). Although in recent years PS-1 has been implicated as a tumor enhancer in various cancers, nothing is known regarding its ro...

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Detalles Bibliográficos
Autores principales:	Li, Ping, Lin, Xi, Zhang, Jun-Rong, Li, Yun, Lu, Jun, Huang, Fei-Chao, Zheng, Chao-Hui, Xie, Jian-Wei, Wang, Jia-Bin, Huang, Chang-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891148/ https://www.ncbi.nlm.nih.gov/pubmed/26872378 http://dx.doi.org/10.18632/oncotarget.7298

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