Expression of two WFDC1/ps20 isoforms in prostate stromal cells induces paracrine apoptosis through regulation of PTGS2/COX-2

BACKGROUND: WFDC1/Prostate stromal 20 (ps20) is a small secreted protein highly expressed within the prostate stroma. WFDC1/ps20 expression is frequently downregulated or lost in prostate cancer (PCa) and ps20 has demonstrated growth-suppressive functions in numerous tumour model systems, although t...

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Detalles Bibliográficos
Autores principales: Hickman, Oliver J, Smith, Richard A, Dasgupta, Prokar, Rao, Sudha Narayana, Nayak, Soumya, Sreenivasan, Shubha, Vyakarnam, Annapurna, Galustian, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891514/
https://www.ncbi.nlm.nih.gov/pubmed/27115470
http://dx.doi.org/10.1038/bjc.2016.91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891514/
https://www.ncbi.nlm.nih.gov/pubmed/27115470
http://dx.doi.org/10.1038/bjc.2016.91

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