Cargando…

Aerosol Delivery of a Candidate Universal Influenza Vaccine Reduces Viral Load in Pigs Challenged with Pandemic H1N1 Virus

Influenza A viruses are a major health threat to livestock and humans, causing considerable mortality, morbidity, and economic loss. Current inactivated influenza vaccines are strain specific and new vaccines need to be produced at frequent intervals to combat newly arising influenza virus strains,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morgan, Sophie B., Hemmink, Johanneke D., Porter, Emily, Harley, Ross, Shelton, Holly, Aramouni, Mario, Everett, Helen E., Brookes, Sharon M., Bailey, Michael, Townsend, Alain M., Charleston, Bryan, Tchilian, Elma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2016
Materias:	Immunotherapy and Vaccines
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891568/ https://www.ncbi.nlm.nih.gov/pubmed/27183611 http://dx.doi.org/10.4049/jimmunol.1502632

Ejemplares similares

Comparison of Heterosubtypic Protection in Ferrets and Pigs Induced by a Single-Cycle Influenza Vaccine
por: Holzer, Barbara, et al.
Publicado: (2018)

Distinct immune responses and virus shedding in pigs following aerosol, intra-nasal and contact infection with pandemic swine influenza A virus, A(H1N1)09
por: Hemmink, Johanneke D., et al.
Publicado: (2016)

Vaccines That Reduce Viral Shedding Do Not Prevent Transmission of H1N1 Pandemic 2009 Swine Influenza A Virus Infection to Unvaccinated Pigs
por: Everett, Helen E., et al.
Publicado: (2021)

Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms
por: McNee, Adam, et al.
Publicado: (2020)

A Novel Murine Cytomegalovirus Vaccine Vector Protects against Mycobacterium tuberculosis
por: Beverley, Peter C. L., et al.
Publicado: (2014)

Timelines of infection and transmission dynamics of H1N1pdm09 in swine
por: Canini, Laetitia, et al.
Publicado: (2020)

Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig
por: Tungatt, Katie, et al.
Publicado: (2018)

Therapeutic Administration of Broadly Neutralizing FI6 Antibody Reveals Lack of Interaction Between Human IgG1 and Pig Fc Receptors
por: Morgan, Sophie B., et al.
Publicado: (2018)

MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria
por: Suliman, Sara, et al.
Publicado: (2019)

IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium
por: Zhang, Yang, et al.
Publicado: (2017)

Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity
por: Nawaf, Maher G., et al.
Publicado: (2017)

CD8 T Cell Tolerance to a Tumor-Associated Self-Antigen Is Reversed by CD4 T Cells Engineered To Express the Same T Cell Receptor
por: Ghorashian, Sara, et al.
Publicado: (2015)

A Nonhuman Primate Scrub Typhus Model: Protective Immune Responses Induced by pKarp47 DNA Vaccination in Cynomolgus Macaques
por: Paris, Daniel H., et al.
Publicado: (2015)

Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines
por: Wang, Chuan, et al.
Publicado: (2016)

Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling
por: Leuthard, Deborah S., et al.
Publicado: (2018)

Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non–Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae
por: Aldon, Yoann, et al.
Publicado: (2020)

Synergistic Effect of Two Nanotechnologies Enhances the Protective Capacity of the Theileria parva Sporozoite p67C Antigen in Cattle
por: Lacasta, Anna, et al.
Publicado: (2021)

B Cells from Aged Mice Do Not Have Intrinsic Defects in Affinity Maturation in Response to Immunization
por: Lee, Jia Le, et al.
Publicado: (2023)

Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma
por: Campal-Espinosa, Ana Cristina, et al.
Publicado: (2023)

Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques
por: White, A. D., et al.
Publicado: (2015)

Clinical Trial of an Oral Live Shigella sonnei Vaccine Candidate, WRSS1, in Thai Adults
por: Pitisuttithum, Punnee, et al.
Publicado: (2016)

Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs
por: Edmans, Matthew, et al.
Publicado: (2021)

Identification of a Newly Conserved SLA-II Epitope in a Structural Protein of Swine Influenza Virus
por: Baratelli, Massimiliano, et al.
Publicado: (2020)

Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study
por: Riddle, Mark S., et al.
Publicado: (2016)

N-Terminal Pfs230 Domain Produced in Baculovirus as a Biological Active Transmission-Blocking Vaccine Candidate
por: Lee, Shwu-Maan, et al.
Publicado: (2017)

Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A
por: Harris, Stephanie A., et al.
Publicado: (2014)

Piliation of Invasive Streptococcus pneumoniae Isolates in the Era before Pneumococcal Conjugate Vaccine Introduction in Malawi
por: Kulohoma, Benard W., et al.
Publicado: (2013)

Distribution of Droplets and Immune Responses After Aerosol and Intra-Nasal Delivery of Influenza Virus to the Respiratory Tract of Pigs
por: Martini, Veronica, et al.
Publicado: (2020)

The major histocompatibility complex homozygous inbred Babraham pig as a resource for veterinary and translational medicine
por: Schwartz, J. C., et al.
Publicado: (2018)

Characterization of T-Cell Responses to Conserved Regions of the HIV-1 Proteome in BALB/c Mice
por: Ondondo, Beatrice, et al.
Publicado: (2014)

IgG Antibody Responses to Recombinant gp120 Proteins, gp70V1/V2 Scaffolds, and a CyclicV2 Peptide in Thai Phase I/II Vaccine Trials Using Different Vaccine Regimens
por: Karasavvas, Nicos, et al.
Publicado: (2015)

Characteristics of patients receiving allergy vaccination: to which extent do socio-economic factors play a role?
por: Petersen, Karin Dam, et al.
Publicado: (2011)

Implications of Differential Age Distribution of Disease-Associated Meningococcal Lineages for Vaccine Development
por: Brehony, Carina, et al.
Publicado: (2014)

Comparative Efficacy of Feline Leukemia Virus (FeLV) Inactivated Whole-Virus Vaccine and Canarypox Virus-Vectored Vaccine during Virulent FeLV Challenge and Immunosuppression
por: Patel, M., et al.
Publicado: (2015)

Toll-Like Receptor Activation by Generalized Modules for Membrane Antigens from Lipid A Mutants of Salmonella enterica Serovars Typhimurium and Enteritidis
por: Rossi, Omar, et al.
Publicado: (2016)

Correlates of Protection against Influenza in the Elderly: Results from an Influenza Vaccine Efficacy Trial
por: Dunning, Andrew J., et al.
Publicado: (2016)

The Carbomer-Lecithin Adjuvant Adjuplex Has Potent Immunoactivating Properties and Elicits Protective Adaptive Immunity against Influenza Virus Challenge in Mice
por: Wegmann, Frank, et al.
Publicado: (2015)

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin
por: Fiaschi, Luigi, et al.
Publicado: (2016)

Subtype C gp140 Vaccine Boosts Immune Responses Primed by the South African AIDS Vaccine Initiative DNA-C2 and MVA-C HIV Vaccines after More than a 2-Year Gap
por: Gray, Glenda E., et al.
Publicado: (2016)

Novel Respiratory Syncytial Virus-Like Particle Vaccine Composed of the Postfusion and Prefusion Conformations of the F Glycoprotein
por: Cimica, Velasco, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0r4ojn5d3rgcdls413iakll1b1