Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae

Influenza virus neuraminidase (NA) is the primary target for influenza therapeutics. Severe complications are often related to secondary pneumonia caused by Streptococcus pneumoniae (pneumococci), which also express NAs. Recently, a NA-mediated lethal synergism between influenza A viruses and pneumo...

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Detalles Bibliográficos
Autores principales: Grienke, Ulrike, Richter, Martina, Walther, Elisabeth, Hoffmann, Anja, Kirchmair, Johannes, Makarov, Vadim, Nietzsche, Sandor, Schmidtke, Michaela, Rollinger, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891693/
https://www.ncbi.nlm.nih.gov/pubmed/27257160
http://dx.doi.org/10.1038/srep27156

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