Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway

The hexosamine biosynthetic pathway (HBP) is a nutrient-sensing metabolic pathway that produces the activated amino sugar UDP-N-acetylglucosamine, a critical substrate for protein glycosylation. Despite its biological significance, little is known about the regulation of HBP flux during nutrient lim...

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Detalles Bibliográficos
Autores principales: Chaveroux, Cédric, Sarcinelli, Carmen, Barbet, Virginie, Belfeki, Sofiane, Barthelaix, Audrey, Ferraro-Peyret, Carole, Lebecque, Serge, Renno, Toufic, Bruhat, Alain, Fafournoux, Pierre, Manié, Serge N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891703/
https://www.ncbi.nlm.nih.gov/pubmed/27255611
http://dx.doi.org/10.1038/srep27278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891703/
https://www.ncbi.nlm.nih.gov/pubmed/27255611
http://dx.doi.org/10.1038/srep27278

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