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An isoform of Nedd4-2 is critically involved in the renal adaptation to high salt intake in mice

Epithelial sodium channels (ENaCs) play critical roles in the maintenance of fluid and electrolyte homeostasis, and their genetic abnormalities cause one type of hereditary salt-sensitive hypertension, Liddle syndrome. As we reported previously, both human and rodent Nedd4L/Nedd4-2 showed molecular...

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Detalles Bibliográficos
Autores principales:	Minegishi, Shintaro, Ishigami, Tomoaki, Kino, Tabito, Chen, Lin, Nakashima-Sasaki, Rie, Araki, Naomi, Yatsu, Keisuke, Fujita, Megumi, Umemura, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891730/ https://www.ncbi.nlm.nih.gov/pubmed/27256588 http://dx.doi.org/10.1038/srep27137

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