The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

The endothelial protein C receptor (EPCR) appears to play an important role in Plasmodium falciparum endothelial cell binding in severe malaria (SM). Despite consistent findings of elevated soluble EPCR (sEPCR) in other infectious diseases, field studies to date have provided conflicting data about...

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Detalles Bibliográficos
Autores principales: Shabani, Estela, Opoka, Robert O., Bangirana, Paul, Park, Gregory S., Vercellotti, Gregory M., Guan, Weihua, Hodges, James S., Lavstsen, Thomas, John, Chandy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891778/
https://www.ncbi.nlm.nih.gov/pubmed/27255786
http://dx.doi.org/10.1038/srep27084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891778/
https://www.ncbi.nlm.nih.gov/pubmed/27255786
http://dx.doi.org/10.1038/srep27084

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