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Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir
Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance and phylogenetic studies suggest a bat origin. The disease is heavily endemic in dromedary ca...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891877/ https://www.ncbi.nlm.nih.gov/pubmed/27255185 http://dx.doi.org/10.1186/s12985-016-0544-0 |
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author | Mohd, Hamzah A. Al-Tawfiq, Jaffar A. Memish, Ziad A. |
author_facet | Mohd, Hamzah A. Al-Tawfiq, Jaffar A. Memish, Ziad A. |
author_sort | Mohd, Hamzah A. |
collection | PubMed |
description | Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance and phylogenetic studies suggest a bat origin. The disease is heavily endemic in dromedary camel populations of East Africa and the Middle East. It is unclear as to when the virus was introduced to dromedary camels, but data from studies that investigated stored dromedary camel sera and geographical distribution of involved dromedary camel populations suggested that the virus was present in dromedary camels several decades ago. Though bats and alpacas can serve as potential reservoirs for MERS-CoV, dromedary camels seem to be the only animal host responsible for the spill over human infections. |
format | Online Article Text |
id | pubmed-4891877 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-48918772016-06-04 Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir Mohd, Hamzah A. Al-Tawfiq, Jaffar A. Memish, Ziad A. Virol J Review Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance and phylogenetic studies suggest a bat origin. The disease is heavily endemic in dromedary camel populations of East Africa and the Middle East. It is unclear as to when the virus was introduced to dromedary camels, but data from studies that investigated stored dromedary camel sera and geographical distribution of involved dromedary camel populations suggested that the virus was present in dromedary camels several decades ago. Though bats and alpacas can serve as potential reservoirs for MERS-CoV, dromedary camels seem to be the only animal host responsible for the spill over human infections. BioMed Central 2016-06-03 /pmc/articles/PMC4891877/ /pubmed/27255185 http://dx.doi.org/10.1186/s12985-016-0544-0 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Mohd, Hamzah A. Al-Tawfiq, Jaffar A. Memish, Ziad A. Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir |
title | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir |
title_full | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir |
title_fullStr | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir |
title_full_unstemmed | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir |
title_short | Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir |
title_sort | middle east respiratory syndrome coronavirus (mers-cov) origin and animal reservoir |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891877/ https://www.ncbi.nlm.nih.gov/pubmed/27255185 http://dx.doi.org/10.1186/s12985-016-0544-0 |
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