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Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia

BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in Russia. Hypertension and hyperlipidemia are important risk factors for CVD that are modifiable by pharmacological treatment and life-style changes. We aimed to characterize the extent of the problem in a typical Russian city b...

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Autores principales: Cybulsky, Marta, Cook, Sarah, Kontsevaya, Anna V., Vasiljev, Maxim, Leon, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891885/
https://www.ncbi.nlm.nih.gov/pubmed/27255373
http://dx.doi.org/10.1186/s12872-016-0300-9
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author Cybulsky, Marta
Cook, Sarah
Kontsevaya, Anna V.
Vasiljev, Maxim
Leon, David A.
author_facet Cybulsky, Marta
Cook, Sarah
Kontsevaya, Anna V.
Vasiljev, Maxim
Leon, David A.
author_sort Cybulsky, Marta
collection PubMed
description BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in Russia. Hypertension and hyperlipidemia are important risk factors for CVD that are modifiable by pharmacological treatment and life-style changes. We aimed to characterize the extent of the problem in a typical Russian city by examining the prevalence, treatment and control rates of hypertension and hyperlipidemia and investigating whether the specific pharmacological regimes used were comparable with guidelines from a country with much lower CVD rates. METHODS: The Izhevsk Family Study II included a cross-sectional survey of a population sample of 1068 men, aged 25–60 years conducted in Izhevsk, Russia (2008–2009). Blood pressure and total cholesterol were measured and self-reported medication use was recorded by a clinician. We compared drug treatments with the Russian and Canadian treatment guidelines for hypertension and hyperlipidemia. RESULTS: The prevalence of hypertension was 61 % (age-standardised prevalence 51 %), with 66 % of those with hypertension aware of their diagnosis and 50 % of those aware taking treatment. 17 % of those taking treatment achieved blood pressure control. The majority (59 %) of those taking treatment were not doing so regularly. Prevalence of hyperlipidemia was 45 % (age-standardised prevalence 40 %), however less than 2 % of those with hyperlipidemia were taking any treatment. Types of lipid-lowering and anti-hypertensive medications prescribed were broadly in line with Russian and Canadian guidelines. CONCLUSION: The prevalence of hypertension and hyperlipidemia is high in Izhevsk while the proportion of those treated and attaining treatment targets is very low. Prescribed medications were concurrent with those in Canada, but adherence is a major issue.
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spelling pubmed-48918852016-06-04 Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia Cybulsky, Marta Cook, Sarah Kontsevaya, Anna V. Vasiljev, Maxim Leon, David A. BMC Cardiovasc Disord Research Article BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in Russia. Hypertension and hyperlipidemia are important risk factors for CVD that are modifiable by pharmacological treatment and life-style changes. We aimed to characterize the extent of the problem in a typical Russian city by examining the prevalence, treatment and control rates of hypertension and hyperlipidemia and investigating whether the specific pharmacological regimes used were comparable with guidelines from a country with much lower CVD rates. METHODS: The Izhevsk Family Study II included a cross-sectional survey of a population sample of 1068 men, aged 25–60 years conducted in Izhevsk, Russia (2008–2009). Blood pressure and total cholesterol were measured and self-reported medication use was recorded by a clinician. We compared drug treatments with the Russian and Canadian treatment guidelines for hypertension and hyperlipidemia. RESULTS: The prevalence of hypertension was 61 % (age-standardised prevalence 51 %), with 66 % of those with hypertension aware of their diagnosis and 50 % of those aware taking treatment. 17 % of those taking treatment achieved blood pressure control. The majority (59 %) of those taking treatment were not doing so regularly. Prevalence of hyperlipidemia was 45 % (age-standardised prevalence 40 %), however less than 2 % of those with hyperlipidemia were taking any treatment. Types of lipid-lowering and anti-hypertensive medications prescribed were broadly in line with Russian and Canadian guidelines. CONCLUSION: The prevalence of hypertension and hyperlipidemia is high in Izhevsk while the proportion of those treated and attaining treatment targets is very low. Prescribed medications were concurrent with those in Canada, but adherence is a major issue. BioMed Central 2016-06-03 /pmc/articles/PMC4891885/ /pubmed/27255373 http://dx.doi.org/10.1186/s12872-016-0300-9 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Cybulsky, Marta
Cook, Sarah
Kontsevaya, Anna V.
Vasiljev, Maxim
Leon, David A.
Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia
title Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia
title_full Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia
title_fullStr Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia
title_full_unstemmed Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia
title_short Pharmacological treatment of hypertension and hyperlipidemia in Izhevsk, Russia
title_sort pharmacological treatment of hypertension and hyperlipidemia in izhevsk, russia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891885/
https://www.ncbi.nlm.nih.gov/pubmed/27255373
http://dx.doi.org/10.1186/s12872-016-0300-9
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