Compromised fidelity of B‐cell tolerance checkpoints in AChR and MuSK myasthenia gravis

OBJECTIVE: Myasthenia gravis (MG) is an autoimmune condition in which neurotransmission is impaired by binding of autoantibodies to acetylcholine receptors (AChR) or, in a minority of patients, to muscle specific kinase (MuSK). There are differences in the dominant IgG subclass, pathogenic mechanism...

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Detalles Bibliográficos
Autores principales: Lee, Jae‐Yun, Stathopoulos, Panos, Gupta, Sasha, Bannock, Jason M., Barohn, Richard J., Cotzomi, Elizabeth, Dimachkie, Mazen M., Jacobson, Leslie, Lee, Casey S., Morbach, Henner, Querol, Luis, Shan, Jing‐Li, Vander Heiden, Jason A., Waters, Patrick, Vincent, Angela, Nowak, Richard J., O'Connor, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891998/
https://www.ncbi.nlm.nih.gov/pubmed/27547772
http://dx.doi.org/10.1002/acn3.311

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