Modulation of natural killer cell functions by interactions between 2B4 and CD48 in cis and in trans

SLAM-related receptors (SRRs) are important modulators of immune cell function. While most SRRs are homophilic, 2B4 (CD244) interacts with CD48, a GPI-anchored protein expressed on many haematopoietic cells. Here we show that natural killer (NK) cell-expressed 2B4 not only binds in trans to CD48 on...

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Detalles Bibliográficos
Autores principales: Claus, Maren, Wingert, Sabine, Watzl, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892432/
https://www.ncbi.nlm.nih.gov/pubmed/27249817
http://dx.doi.org/10.1098/rsob.160010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892432/
https://www.ncbi.nlm.nih.gov/pubmed/27249817
http://dx.doi.org/10.1098/rsob.160010

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