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MicroRNA-27 Prevents Atherosclerosis by Suppressing Lipoprotein Lipase-Induced Lipid Accumulation and Inflammatory Response in Apolipoprotein E Knockout Mice
Atherosclerotic lesions are lipometabolic disorder characterized by chronic progressive inflammation in arterial walls. Previous studies have shown that macrophage-derived lipoprotein lipase (LPL) might be a key factor that promotes atherosclerosis by accelerating lipid accumulation and proinflammat...
Autores principales: | Xie, Wei, Li, Liang, Zhang, Min, Cheng, Hai-Peng, Gong, Duo, Lv, Yun-Cheng, Yao, Feng, He, Ping-Ping, Ouyang, Xin-Ping, Lan, Gang, Liu, Dan, Zhao, Zhen-Wang, Tan, Yu-Lin, Zheng, Xi-Long, Yin, Wei-Dong, Tang, Chao-Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892477/ https://www.ncbi.nlm.nih.gov/pubmed/27257686 http://dx.doi.org/10.1371/journal.pone.0157085 |
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